Social media footage showed motorists battling through muddy floodwater in the southern state of Parana before the disaster.
After a landslide covered a highway in southern Brazil, at least two people have been killed and scores are missing.
Heavy precipitation triggered a mudslide on the BR-376 highway in Guaratuba, Parana state.
The location of approximately 30 individuals is unknown.
Multiple automobiles are believed to be buried in the debris on the coastal road.
Aerial photographs also depict trucks on their sides and dangling precariously over the brink of the freeway.
Before the disaster, cars were shown on video battling through murky floodwater.
Some online users have questioned why the route was not closed sooner.
As a result of the landslide on Tuesday, access to a major grain and sugar terminal was restricted.
About 80% of exports from Paranagua, the second-largest grain, and sugar port in the country, are transported by truck.
After the avalanche, the BR-277 road leading to the Paranagua and Antonia ports was closed but was scheduled to reopen last night.
The port authorities have declined to provide a loss estimate.
At Paranagua, operators and terminals are moving products that are expected to last till this weekend.
A few days before, a landslide in southern Italy killed at least three people, including a small girl thought to be five years old, on the island of Ischia.
