If you’ve been depressed recently, it could be an indication that you’re at risk for a stroke.

In the years preceding the onset of one, individuals are more likely to feel lonely, depressed, and exhausted, according to research.

After a stroke, depression symptoms are prevalent, but experts want more research to determine if they might serve as an early warning sign.

However, the impact of stress-induced inflammation on blood vessels may be a contributing factor.

Depression is not only a post-stroke issue but also a pre-stroke occurrence, according to lead author Maria Blochl of the Germany’s University of Münster.

Even minor increases in depressive symptoms, particularly mood and fatigue-related symptoms, may indicate an impending stroke.

The study followed 10,000 older persons without a history of stroke for more than a decade.

Every two years, participants were assessed about their mood and given a score based on the number of depression-like symptoms they exhibited.

Researchers discovered that patients with stroke were more likely to have a higher score two years before the onset of the ailment.

Dr. Blochl continued, “Depression is one of the most pressing issues for stroke survivors, and it is so prevalent that it is known as post-stroke depression.”

‘However, according to our research, not only can depression symptoms increase significantly after stroke, but some had already developed some depressive symptoms before the stroke happened.’

10 797 adults with an average age of 65 were observed for up to 12 years by researchers. During that time, 425 strokes occurred.

They were matched with 4,249 individuals of similar age, gender, ethnicity, and other health conditions who did not have one.

Every two years, participants were asked whether they had experienced depressive symptoms in the previous week.

These included feelings of depression, loneliness, sadness, or that everything was an effort, as well as restless sleep.

Participants received a higher score the more symptoms they exhibited.

Six years before a stroke, researchers observed no change in scores, with both groups scoring approximately 1.6 points.

Those who did suffer one, however, scored an average of 0.33 points higher than those who did not two years prior.

Dr. Blochl remarked, ‘It is uncertain whether these pre-stroke changes can be used to predict who will experience a stroke.

The future study must investigate precisely why depression symptoms develop before the stroke.

In addition, the study demonstrates why clinicians must conduct long-term monitoring for depression symptoms in stroke survivors.

The researchers also examined whether stroke patients were more likely to have been diagnosed with depression before the complication.

In the years preceding a stroke, patients were 5% more likely to develop clinical depression than their peers.

Dr. Blochl stated, “This shows that increasing symptoms of depression preceding a stroke are predominantly modest and may not always be clinically identifiable.”

Ischemic strokes occur when the brain loses its blood supply, typically due to a blood clot in a blood vessel.

Less frequent hemorrhagic strokes occur when a blood vessel ruptures, filling the brain with an excessive amount of blood while depriving other parts of the appropriate supply.

Approximately one-third of stroke victims eventually develop depression, which is frequently triggered by biochemical abnormalities in the brain.

In certain instances, however, it is a psychological response to the physical shock of a stroke.

Depression increases the risk of developing heart disease or suffering a stroke later in life, according to a study conducted by the University of Cambridge in 2020 on half a million Britons.

Depression could be a marker of a general decline in health, however, its causes remain unclear.